Detalles de la búsqueda
1.
Biosynthesis of a new skyllamycin in Streptomyces nodosus: a cytochrome P450 forms an epoxide in the cinnamoyl chain.
Org Biomol Chem
; 22(14): 2835-2843, 2024 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38511621
2.
Structure-Function Analysis of the Essential Mycobacterium tuberculosis P450 Drug Target, CYP121A1.
Int J Mol Sci
; 25(9)2024 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38732102
3.
Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s.
J Biol Chem
; 298(4): 101746, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35189143
4.
An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury.
EMBO Rep
; 22(8): e52785, 2021 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34224201
5.
Characterization of a flexible AAV-DTR/DT mouse model of acute epithelial lung injury.
Am J Physiol Lung Cell Mol Physiol
; 323(2): L206-L218, 2022 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35762632
6.
Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.
Mol Biol Evol
; 38(3): 952-967, 2021 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33031537
7.
On the occurrence of cytochrome P450 in viruses.
Proc Natl Acad Sci U S A
; 116(25): 12343-12352, 2019 06 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31167942
8.
RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma.
Respir Res
; 22(1): 158, 2021 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34022896
9.
The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs.
Respir Res
; 22(1): 48, 2021 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33557843
10.
Active and Passive Electro-Optical Sensors for Health Assessment in Food Crops.
Sensors (Basel)
; 21(1)2020 Dec 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33383831
11.
Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): 10-year results from a randomised, phase 3, factorial trial.
Lancet Oncol
; 20(2): 267-281, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30579763
12.
FKBP51 modulates steroid sensitivity and NFκB signalling: A novel anti-inflammatory drug target.
Eur J Immunol
; 48(11): 1904-1914, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30169894
13.
Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus.
Biochim Biophys Acta Proteins Proteom
; 1866(1): 155-165, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28694077
14.
Time on androgen deprivation therapy and adaptations to exercise: secondary analysis from a 12-month randomized controlled trial in men with prostate cancer.
BJU Int
; 121(2): 194-202, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28872752
15.
Neutralization of both IL-1α/IL-1ß plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice.
Pulm Pharmacol Ther
; 44: 96-105, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28315490
16.
The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction.
Arterioscler Thromb Vasc Biol
; 36(6): 1247-53, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27102960
17.
Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.
J Biol Chem
; 290(39): 23916-34, 2015 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26269599
18.
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.
J Pharmacol Exp Ther
; 357(3): 554-61, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27048659
19.
Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.
Mol Phylogenet Evol
; 94(Pt B): 676-687, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26432395
20.
Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.
Toxicol Appl Pharmacol
; 296: 73-84, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26853319